Research Summary

• How do proteins and RNA molecules fold? How do ions and ligands bind to biomolecules? What are the roles of water, ions, and co-solutes in these processes? Members of the Sorin Lab study the structure and dynamics of biological molecules via computation and simulation. Using cluster computing and the Folding@Home Distributed Computing Project, we can apply a variety of models and methods to sample large numbers of independent simulations. Indeed, we are now capable of simulating such events in dynamic equilibrium, making simulation a powerful tool with which to probe such topics and collaborate with experiment. Learn more about our research interests and projects.

Students Wanted!

• Physics, chemistry, biochem, biology, math/stats, and CS students wanted! If you find computation fun, interesting, or both, then there are many projects available involving molecular simulation and modeling in which you can participate. Regardless of your major and computational experience, we can find something challenging and interesting to work on, and ideas for new projects or extensions of current projects are always welcome. In particular, I am currently seeking a computer science major with interest in scientific computing to work on establishing laboratory code. If you're a motivated student interested in participating in a fun research group doing exciting & highly interdisciplinary research, click here for more info!

Teaching Assignments & Interests

• CHEM 377A: Fundamentals of Physical Chemistry I
• CHEM 480/580: Biomolecular Modeling & Simulation
• Introductory, general, and physical chemistry
• Computational chemistry, biochemistry, & biophysics
• Integration of computational resources into science education
• Tools in scientific research and education